Monday, 6 November 2017

Compression and Compaction Full Chapter Industrial Pharmacy PDF

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Powdered solids are heterogeneous because they are composed of individual particles of widely differing sizes, shape and air spaces.
So it is virtually impossible to characterize these complex systems fully in terms of fundamental properties at two levels namely those associated with an individual particles and those of bulk powder are of interest.
Compaction is the situation in which the materials are subjected to some level of  mechanical forces.

The effects of these forces are particularly important in the manufacture of tablets and granules, in the filling of hard shell gelatin capsules, in the powder handling.

Some Basic Definitions 

Compaction 
it is defined as ‘compression, consolidation ’of a two- phase (particulate solid-  gas) system due to the applied force .
COMPRESSION :
A reduction in the bulk volume of the material as a result of displacement of  the gaseous phase.
      
 CONSOLIDATION:
Increase in the mechanical strength of the material resulting from particle-particle interactions. 

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